Aston Villa beat champions Manchester City Wednesday to extend their remarkable winning run at home as Liverpool closed to within two points of leaders Arsenal with victory at Sheffield United.
Elsewhere on a busy program in the English top flight, Scott McTominay scored twice as Manchester United beat Chelsea 2-1 and Fulham hammered Nottingham Forest 5-0, heaping the pressure on manager Steve Cooper.
Marcus Rashford paid for his slump in form as the United star was dropped to the bench by Erik ten Hag for the match against Chelsea at Old Trafford.
But in his absence United secured a priceless three points, shrugging off a rare penalty miss from Bruno Fernandes in the first half.
Chelsea's Cole Palmer finished an impressive team move on the stroke of half-time to cancel out McTominay's opener.
But the Scotland international headed home Alejandro Garnacho's cross for his second with about 20 minutes to lift to United to sixth in the table, just three points behind City.
Mauricio Pochettino's Chelsea have now lost six games this season and are stuck in mid-table.
Forest, in their second season back in the Premier League, slumped to a fourth straight defeat at Fulham.
Alex Iwobi and Raul Jimenez scored two goals apiece and Tom Cairney completed the humiliation in the final minutes.
Brighton and Hove Albion recorded a 2-1 home win against Brentford courtesy of goals from Pascal Gross and Jack Hinshelwood.
Bournemouth notched their third win in four games, with Marcos Senesi and Kieffer Moore on the scoresheet at Palace.
Villa, who have now won 14 league games in a row at home, scored the only goal of the game in the 74th minute, when Leon Bailey's shot took a huge deflection off Ruben Dias.
Pep Guardiola's men, aiming for an unprecedented fourth consecutive top-flight title, are now winless in four games and five points behind leaders Arsenal.
Last year's treble winners, missing the suspended Rodri, have now won just three league games in nine.
Liverpool, looking increasingly dangerous, saw off basement club Sheffield 2-0.