Real Madrid and Bayern Munich were among the clubs to qualify for the last 16 of the Champions League with two group games to spare on Wednesday.
Last season’s runners-up Inter Milan and Real Sociedad also secured their tickets for the knockout phase, joining holders Manchester City and RB Leipzig in advancing to the last 16.
Madrid, the record 14-time European champions, made sure of their progress from Group C with a 3-0 home win over Braga after surviving an injury setback just before kick-off.
Goalkeeper Kepa Arrizabalaga pulled out hurt in the warm-up, but his replacement Andriy Lunin excelled by saving Alvaro Djalo's sixth-minute penalty.
With Jude Bellingham rested, Brahim Diaz gave Real a 27th-minute lead before Brazilian duo Vinicius Junior and Rodrygo both scored in the second half.
Napoli are poised to go through from the group alongside Real despite being held to a 1-1 draw at home by Union Berlin.
Matteo Politano put Napoli ahead late in the first half but David Datro Fofana, on loan from Chelsea, equalised soon after the restart.
The result allowed Union to end a 12-game losing run but they cannot now qualify for the last 16.
Their Bundesliga rivals Bayern qualified with a 2-1 victory at home to Galatasaray, their 17th consecutive win in the Champions League group stage.
Thomas Tuchel's side saw Galatasaray have a goal disallowed for offside before Harry Kane headed in the opener with just 10 minutes left.
Kane then added another, his 19th goal already for Bayern in just 15 appearances, before Cedric Bakambu pulled one back in stoppage time for Galatasaray.
Galatasaray still stand every chance of going through from Group A after United lost in a remarkable game in Denmark.
Meanwhile, Arsenal are on the brink of progressing from Group B after a 2-0 home win over Sevilla, in which Bukayo Saka set up Leandro Trossard for the opener in the first half, and then added the second after the break.
The Gunners are four points ahead of both Lens and PSV Eindhoven, with the Dutch side boosting their own hopes by beating the French side 1-0 thanks to Luuk de Jong's early header.
Lens had substitute Morgan Guilavogui sent off late on.
In Group D, Inter secured their progress with a 1-0 win away to Red Bull Salzburg in Austria, a game settled by a late Lautaro Martinez penalty.
That result also allowed Real Sociedad to qualify after their earlier 3-1 defeat of Portuguese giants Benfica, who have lost all four matches in the group.
Arsenal are within touching distance of qualifying for the Champions League knockout stages after Leandro Trossard and Bukayo Saka clinched a 2-0 win against Sevilla on Wednesday.
Mikel Arteta's side got back on track after successive domestic defeats thanks to Trossard's first half opener and Saka's strike after the break at the Emirates Stadium.
Lautaro Martinez shot Inter Milan into the last 16 of the Champions League with the only goal in Wednesday's 1-0 win at Salzburg, continuing his red-hot scoring form.
Argentina forward Martinez confidently fired home from the penalty spot with four minutes remaining at the Stadion Salzburg to secure passage to the knockout stage of Europe's top club tournament.