Luis Suarez and Lionel Messi were on target as Inter Miami marched into the last eight of the CONCACAF Champions Cup with a 3-1 (5-3 aggregate) win over Nashville on Wednesday.
Messi set up Suarez for the eighth-minute opener and then the Argentine found the target himself in the 23rd minute.
But the eight-times Ballon d'Or winner was substituted in the 50th minute before his replacement Robert Taylor made sure of the victory with a 63rd-minute header.
Miami, playing in the competition for the first time, will face the winner of Thursday's second-leg between Mexico's Monterrey and MLS's FC Cincinnati in the quarter-finals.
The Liga MX team are at home and lead 1-0 from the first-leg.
The first-leg in Tennessee had seen Nashville take a two-goal lead before goals from Messi and Suarez inspired a comeback for a 2-2 draw.
And it was the former Barcelona pair that proved to be the difference again as Miami took control from the outset.
Messi had an early opportunity when he was brought down on the edge of the box, providing him with a free-kick from a central position but his shot struck the wall.
But minutes later, Messi created the opener, splitting the Nashville defence with a perfect pass to Suarez whose exquisite finish, with the outside of his right foot, matched the precision of the assist.
While the veteran quartet of Barcelona players in the Miami team, also including Spaniards Jordi Alba and Sergio Busquets, grab the attention, the young midfield workhouse Diego Gomez has become increasingly influential.
It was the Paraguayan's aggressive running that created the second goal, in the 23rd minute, when Gomez drove aggressively into the box and then smartly slipped inside to Messi who buried the ball, first time, into the corner.
Nashville had created little but they offered a wake-up call to Miami keeper Drake Callender when Daniel Lovitz blasted a left-foot volley against the post.
Miami coach Gerardo Martino brought Messi off for Taylor five minutes after the interval, with no visible sign of an injury for the Argentine.
The departure of the eight-time Ballon d'Or winner gave Nashville a lift and they began to attack with real intent and Callender had to pull off a fine save at point blank range to deny Lukas MacNaughton.