Reigning Serie A champions Inter Milan reclaimed top spot on Saturday after beating Roma 3-1 at home to move one point clear of AC Milan.
Denzel Dumfries and Marcelo Brozovic scored first-half goals at San Siro before Lautaro Martinez headed in a third shortly after the break to earn Inter a fourth consecutive win.
Henrikh Mkhitaryan drilled in a late consolation as Inter capped off a successful week that began with a 3-0 victory Tuesday over Milan in the second leg of their Italian Cup semi-final.
Milan could regain first place by winning at Lazio on Sunday, but Inter have a game in hand away to Bologna in midweek.
Third-placed Napoli on Sunday play an Empoli side who are winless in 16 matches since they defeated Luciano Spalletti's title challengers 1-0 in Naples on December 12.
Jose Mourinho's Roma arrived in Milan unbeaten in 12 games, a run which had given them an outside shot of qualifying for the Champions League.
They dampened Napoli's Scudetto hopes at the start of the week by snatching a last-gasp equaliser in a 1-1 draw, but Inter ensured
there was no such slip-up against the man who led them to the treble in 2010.
