Barcelona will be looking for their sixth straight win in all competitions when they welcome Mallorca to Camp Nou on Saturday night, report agencies.
Barca will again be without the services of full-backs Nelson Semedo and Jordi Alba through injury, while Ousmane Dembele is out until the early stages of 2020 with a hamstring problem.
The Spanish champions have no fresh injury concerns from the win over Atletico last weekend, though, while Sergio Busquets is available having missed out against Atletico through suspension.
There are not expected to be many alterations from the team that started against Diego Simeone's side, with Antoine Griezmann again joining Luis Suarez and Messi in the final third.
Messi will take to the field for the first time since winning his sixth Ballon d'Or crown, with the Argentine pipping Liverpool's Virgil van Dijk to the individual honour earlier this week.
Gerard Pique had to be substituted against Atletico after picking up a heavy blow to his knee, but the centre-back is available to take to the field this weekend.
As for Mallorca, Lumor Agbenyenu is suspended after being sent off against Betis last weekend, while Cucho Hernandez and Iddrisu Baba are on the sidelines through injury.
Josep Sene and Junior Lago could both come into the starting team, while there should once again be a spot for on-loan Real Madrid midfielder Takefusa Kubo.