Although bacterial infections are the most common cause of cystitis, a number of noninfectious factors also may cause the bladder to become inflamed. Some examples include:
• Interstitial cystitis: The cause of this chronic bladder inflammation, also called painful bladder syndrome, is unclear. Most cases are diagnosed in women. The condition can be difficult to diagnose and treat.
• Drug-induced cystitis: Certain medications, particularly the chemotherapy drugs cyclophosphamide and ifosfamide, can cause inflammation of your bladder as the broken-down components of the drugs exit your body.
• Radiation cystitis: Radiation treatment of the pelvic area can cause inflammatory changes in bladder tissue.
• Foreign-body cystitis: Long-term use of a catheter can predispose you to bacterial infections and to tissue damage, both of which can cause inflammation.
• Chemical cystitis: Some people may be hypersensitive to chemicals contained in certain products, such as bubble bath, feminine hygiene sprays or spermicidal jellies, and may develop an allergic-type reaction within the bladder, causing inflammation.
• Cystitis associated with other conditions: Cystitis may sometimes occur as a complication of other disorders, such as diabetes, kidney stones, an enlarged prostate or spinal cord injuries.
Courtesy: Mayo Clinic